Pharmacogenomics and Genomic Medicine Group
2026
Ryabinina, O., Twum, J. A., Anyimadu, J., Addison, H. K., Amoako, J. P., Nyarko, S. B., & Thomford, N. E. (2026). Age-related Variations in Clinical and Biochemical Profiles of People Living with HIV. AIDS Research and Treatment. https://doi.org/10.1155/arat/1670270
Ryabinina, O., Addo, F.O., Thomford, N.E. et al. Antihypertensive medication adherence and associated risk factors among adults with hypertension: a cross-sectional study in a teaching hospital, Ghana. BMC Cardiovasc Disord 26, 156 (2026). https://doi.org/10.1186/s12872-025-05410-3
2025
Thomford, N.E., Kellermann, T., Twum, J.A. et al. Drug-drug interaction between dolutegravir and artemether-lumefantrine in HIV and malaria mono- and co-infections: a pharmacogenetic analysis from Ghana. AIDS Res Ther 22, 85 (2025). https://doi.org/10.1186/s12981-025-00787-9
Thomford, N.E., Ryabinina, O., Twum, J.A. et al. Cohort profile: the pharmacogenomics and pharmacokinetics study in Ghanaian HIV patients (GenoPharm-GH). BMC Genom Data 26, 88 (2025). https://doi.org/10.1186/s12863-025-01369-4
2024
Thomford, N.E., Kellermann, T., Biney, R.P. et al. Therapeutic efficacy of generic artemether–lumefantrine in the treatment of uncomplicated malaria in Ghana: assessing anti-malarial efficacy amidst pharmacogenetic variations. Malar J 23, 125 (2024). https://doi.org/10.1186/s12936-024-04930-1
Thomford N.E., Abraham S.A., Nyarko Badu S., Biney R.P. A consideration of CYP2D6 genetic variations in the Ghanaian population as a potential ‘culprit’ for the tramadol “abuse crisis”. BMC Medical Genomics, 2024, 17:28, 1 6. https://doi.org/10.1186/s12920-023-01773-8
2023
Thomford N.E., Adu F., Gavor-Kwashi C., Nyarko S.B., Nsiah P., Ephraim R.D., Adjei G., Anyanful A. An exploratory pharmacogenetic screening of SLC22A6, SLC22A8, ABCC4 and ABCC10 genes in a cohort of Ghanaian HBV patients. Egyptian Journal of Medical Human Genetics. 2023 24:50. https://doi.org/10.1186/s43042-023-00428-8
Thomford NE, Dampson FN, Adjei G, Eliason S, Ekor M, Kyei GB. Psychometric assessment of hiv stigma in patients attending a tertiary facility: an initial validation of the Berger HIV stigma scale in a Ghanaian perspective. PLoS ONE 18(4): e0282193. https://doi.org/10.1371/ journal.pone.0282193
Thomford NE, Anyanful A, Ateko RO, Blackhurst D, Biney RP, Boadi D, Nyarko SB, Ekor M, Kyei GB. Apolipoprotein E genetic variation, atherogenic index and cardiovascular disease risk assessment in an African population: An analysis of HIV and malaria patients in Ghana. PLoS ONE 18(5): e0284697. https://doi.org/10.1371/journal. pone.0284697
Osafo C., Thomford N.E., Coleman J., Carboo A., Guure C., Okyere P, et al. (2022) APOL1 genotype associated risk for preeclampsia in African populations: Rationale and protocol design for studies in women of African ancestry in resource limited settings. PLoS ONE. 2023 17(12): e0278115. https://doi.org/10.1371/journal. pone.0278115
Sarpong E, Acheampong D.O., Fordjour G.N.R., Anyanful A., Aninagyei E., Tuoyire D.A., Blackhurst D., Kyei G.B., Ekor M., Thomford N.E. Zero malaria: A mirage or reality for a population of sub-Saharan Africa in health transition. Malaria Journal. 2022. 21(1),314
2022
Osafo C, Thomford NE, Coleman J,Carboo A, Guure C, Okyere P, et al. (2022) APOL1 genotype associated risk for preeclampsia in African populations: Rationale and protocol design for studies in women of African ancestry in resource limited settings. PLoS ONE 17(12): e0278115. https://doi.org/10.1371/journal. pone.0278115
2021
Kuguyo O., Dube Mandishora R.S., Thomford N.E., Makunike-Mutasa R., Nhachi C.F.B., Matimba A., Dandara C. High-risk HPV genotypes in Zimbabwean women with cervical cancer: Comparative analyses between HIV-negative and HIV-positive women. PLoS One. 2021; 16(9):e0257324. doi:10.1371/journal.pone.0257324. eCollection 2021
Adjei G., Enuameh Y.A., Thomford N.E. Prevalence of COVID-19 genomic variation in Africa: a living systematic review protocol. JBI Evid Synth. 2021 Aug 2. doi: 10.11124/JBIES-20-00516 2020
Thomford N.E., Mhandire D., Dandara C., Kyei G.B. Promoting Undetectable Equals Untransmittable in Sub-Saharan Africa: Implication for Clinical Practice and ART Adherence. Int J Environ Res Public Health. 2020 Aug 25;17(17): E6163. doi: 10.3390/ijerph17176163.
Thomford N.E., Yahaya E.S., Ekor M., Awortwe C. Turning Up the Volume for Precision Herbal Medicine in Africa in an Era of COVID-19 and Planetary Biodiversity Loss. OMICS. 2020 Aug 21. doi: 10.1089/omi.2020.0150
Thomford, N. E., Biney, R. P., Okai, E., Anyanful, A., Nsiah, P., Frimpong, P. G., . . . Wonkam, A. (2020). Clinical Spectrum of congenital heart defects (CHD) detected at the child health Clinic in a Tertiary Health Facility in Ghana: a retrospective analysis. BMC Journal of Congenital Cardiology, 4(1), 3. doi:10.1186/s40949-020-00034-y Yılmaz S.G., Bozkurt H., Ndadza A.,
Thomford N.E., Karaoğlan M., Keskin M., Benlier N.,Dandara. Childhood obesity risk in relation to circulating miRNAs targeting the perilipin 1 (PLIN1) gene. OMICS: A journal of integrative biology 24(1):43-50. doi: 10.1089/omi.2019.0150. Epub 2019
2019
Thomford N.E., Bope C.D., Agamah F.E., Dzobo K., Owusu Ateko R., Chimusa E., Mazandu G.K., Ntumba S.B., Dandara C., Wonkam A. Implementing Artificial Intelligence and Digital Health in Resource-Limited Settings? Top 10 Lessons We Learned in Congenital Heart Defects and Cardiology. OMICS: A journal of integrative biology doi: 10.1089/omi.2019.0142 Dandara C., Thomford N.E., Tashinga E.B. Herbal Remedies: Throwing Off Phenotype Prediction—A Culprit for Pharmacogenomic‐Guided Drug Therapy and Drug Safety. Clin Pharmacol Ther. 106(2):302-304. doi: 10.1002/cpt.1509
Awany D., Allali I., Dalvie S., Hemmings S., Mwaikono K.S., Thomford N.E., Gomez A., Mulder N. and Chimusa E.R. Host and Microbiome Genome-Wide Association Studies: Current State and Challenges. Front. Genet. 2019. 9:637. doi: 10.3389/fgene.2018.00637