Pharmacogenomics and Genomic Medicine Group
ABOUT US
The Pharmacogenomics and Genomic Medicine Group (PGMG) conducts research in pharmacogenomics, pharmacology and the genomic basis of disease in African populations. Our work spans natural product drug discovery, drug metabolism and genomic susceptibility to disease.
We particularly seek to:
- Understand genomic variation in drug response across African populations
- Characterise host immune genetics and how it shapes infectious disease outcomes and progression
- Identify genomic signatures associated with non-syndromic sporadic congenital heart defects
- Map the genomic architecture of rare diseases
- Explore how the pharmacomicrobiome influences disease outcomes and response to treatment
Our overarching goal is to translate our findings into better treatment and management for patients. Working with our collaborators, we study human biological samples, including blood, serum, plasma and stool, to answer these questions.
Our Collaborators
- Dr George Boateng Kyei, Noguchi Memorial Institute for Medical Research, University of Ghana, Accra, Ghana
- Dr Tracy Kellerman, Stellenbosch University, Cape Town, South Africa
- Dr Kevin Dzobo, University of Cape Town, South Africa
- Prof. Collet Dandara, University of Cape Town, South Africa
- Prof. Ambroise Wonkam, University of Cape Town, South Africa and John Hopkins University, USA
- Dr Charlotte Osafo, University of Ghana Medical School, Ghana
- Dr Justin Komguep Nono, Ministry of Scientific Research and Innovation, Cameroon
- Prof. Bruce Carleton, University of British Columbia, Vancouver, Canada
Our Funders & Supporters
