Pharmacogenomics and Genomic Medicine Group

Phone: +233 594972150 | Email: nthomford@ucc.edu.gh/nicholas.thomford@uct.ac.za

PUBLICATION

We are a research group that is made of researchers from different disciplines bringing their expertise to undertake research projects in pharmacogenomics…

Selected publications

2023

Thomford NE, Dampson FN, Adjei G, Eliason S, Ekor M, Kyei GB. Psychometric assessment of hiv stigma in patients attending a tertiary facility: an initial validation of the Berger HIV stigma scale in a Ghanaian perspective. PLoS ONE 18(4): e0282193. https://doi.org/10.1371/ journal.pone.0282193

 

Thomford NE, Anyanful A, Ateko RO, Blackhurst D, Biney RP, Boadi D,  Nyarko SB, Ekor M, Kyei GB. Apolipoprotein E genetic variation, atherogenic index and cardiovascular disease risk assessment in an African population: An analysis of HIV and malaria patients in Ghana. PLoS ONE 18(5): e0284697. https://doi.org/10.1371/journal. pone.0284697

2022

Osafo C, Thomford NE, Coleman J,Carboo A, Guure C, Okyere P, et al. (2022) APOL1

genotype associated risk for preeclampsia in African populations: Rationale and protocol design for studies in women of African ancestry in resource limited settings. PLoS ONE 17(12): e0278115. https://doi.org/10.1371/journal. pone.0278115

2021

Kuguyo O., Dube Mandishora R.S., Thomford N.E., Makunike-Mutasa R., Nhachi C.F.B., Matimba A., Dandara C. High-risk HPV genotypes in Zimbabwean women with cervical cancer: Comparative analyses between HIV-negative and HIV-positive women. PLoS One. 2021; 16(9):e0257324. doi:10.1371/journal.pone.0257324. eCollection 2021

Adjei G., Enuameh Y.A., Thomford N.E. Prevalence of COVID-19 genomic variation in Africa: a living systematic review protocol. JBI Evid Synth. 2021 Aug 2. doi: 10.11124/JBIES-20-00516

2020

Thomford N.E., Mhandire D., Dandara C., Kyei G.B. Promoting Undetectable Equals Untransmittable in Sub-Saharan Africa: Implication for Clinical Practice and ART Adherence. Int J Environ Res Public Health. 2020 Aug 25;17(17): E6163. doi:
10.3390/ijerph17176163.

Thomford N.E., Yahaya E.S., Ekor M., Awortwe C. Turning Up the Volume for Precision Herbal Medicine in Africa in an Era of COVID-19 and Planetary Biodiversity Loss. OMICS. 2020 Aug 21. doi: 10.1089/omi.2020.0150.

Thomford, N. E., Biney, R. P., Okai, E., Anyanful, A., Nsiah, P., Frimpong, P. G., . . . Wonkam, A. (2020). Clinical Spectrum of congenital heart defects (CHD) detected at the child health Clinic in a Tertiary Health Facility in Ghana: a retrospective analysis. BMC
Journal of Congenital Cardiology, 4(1), 3. doi:10.1186/s40949-020-00034-y

Yılmaz S.G., Bozkurt H., Ndadza A., Thomford N.E., Karaoğlan M., Keskin M., Benlier N.,Dandara. Childhood obesity risk in relation to circulating miRNAs targeting the perilipin 1 (PLIN1) gene. OMICS: A journal of integrative biology 24(1):43-50. doi: 10.1089/omi.2019.0150. Epub 2019

2019

Thomford N.E., Bope C.D., Agamah F.E., Dzobo K., Owusu Ateko R., Chimusa E.,
Mazandu G.K., Ntumba S.B., Dandara C., Wonkam A. Implementing Artificial Intelligence
and Digital Health in Resource-Limited Settings? Top 10 Lessons We Learned in
Congenital Heart Defects and Cardiology. OMICS: A journal of integrative biology doi:
10.1089/omi.2019.0142

Dandara C., Thomford N.E., Tashinga E.B. Herbal Remedies: Throwing Off Phenotype
Prediction—A Culprit for Pharmacogenomic‐Guided Drug Therapy and Drug Safety. Clin
Pharmacol Ther. 106(2):302-304. doi: 10.1002/cpt.1509

Awany D., Allali I., Dalvie S., Hemmings S., Mwaikono K.S., Thomford N.E., Gomez A.,
Mulder N. and Chimusa E.R. Host and Microbiome Genome-Wide Association Studies:
Current State and Challenges. Front. Genet. 2019. 9:637. doi: 10.3389/fgene.2018.00637

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